Tackle your toughest cold and flu symptoms with Tylenol Cold + Flu Severe Caplets. This multi-symptom formula provides temporary relief of minor aches and pains, fever, headache, sore throat, nasal and chest congestion, and cough. Each caplet contains 325 mg of acetaminophen to relieve pain and reduce fever, 10 mg of dextromethorphan to suppress cough, 5 mg of phenylephrine to reduce nasal congestion, and 200 mg of the expectorant guaifenesin to help make coughs more productive.